E - Gard Paste
omeprazole 37%w/w
Heals ulcer, Restores performance
Omeprazole is a gastric acid pump inhibitor that regulates the final step in hydrogen ions production and blocks gastric acid secretion regardless of the stimulus. Omeprazole irreversibly binds to the gastric parietal cell H, K. ATPase enzyme which pumps hydrogen ions into the lumen of the stomach in exchange for potassium ions. Since omeprazole accumulates in the cell cannaliculi and is irreversibly bound to the effect site, the plasma concentration at steady state is not directly related to the amount that is bound to the enzyme.
The relationshiop between omeprazole action and plasma concentration is a function of the rate-limiting process of H, K. AT Paste activity/turnover.
Once all of the enzyme becomes bound, acid secretion resumes only after new H, K. AT Paste is synthesized in the parietal cell (i.e., the rate of new enzyme synthesis exceeds the rate of inhibition).
INDICATIONS
For treatment and prevention of recurrence of gastric ulcers in horses and foals 4 weeks of age and older.
DIRECTION FOR USE
E-Gard Paste for horses is recommended for use in horses and foals 4 weeks of age and older.The contents of one syringe will dose a 1250lb (568kg) horse at the rate of the syringe plunger will deliver sufficient omeprazole to treat 250lb (114kg) body weight. For prevention of recurrence of gastric ulcers, each weight marking will deliver sufficient omeprazole to dose 500lb (227kg) body weight.
2 comments:
can anybody give price details and manufactures details of E-gard paste
i tried it. you should better use gastrogard. Omeprazole needs a special surrounding (galenic) to be absorbed in the duodenum. furthermore this e-gard is an illegal drug in several countries.
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